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Selected Bibliography on Nuclear Pharmacy Practice


Purpose | Regulatory | Product Monographs | Textbooks
Continuing Education Programs | Journal Articles


The American Pharmaceutical Association
Academy of Pharmacy Practice & Management
Nuclear Pharmacy Practice Section

SELECTED BIBLIOGRAPHY ON NUCLEAR PHARMACY PRACTICE

(currently out-of-date: last revised 9-1-94)

PURPOSE

In preparing for the Nuclear Pharmacy Specialty Examination, familiarity with a broad range of nuclear pharmacy-related topics is advisable. Although nuclear pharmacists possess knowledge in many topic areas from their training and experience, knowledge in some topic areas may be deficient due to its recency and/or its lack of applicability in the pharmacist's specific practice setting. Therefore, as an aid in the preparation for the Specialty Examination, the Scientific and Professional Affairs Committee of the Section on Nuclear Pharmacy Practice of the American Pharmaceutical Association has compiled this selected bibliography. These publications were chosen to highlight many knowledge areas that are generally considered to be important in the practice of nuclear pharmacy in a variety of settings. This listing is not intended to be complete, but merely provides a sampling of information from various sources.

No guarantee, implied or otherwise, is made that knowledge contained in these sources will ensure successful matriculation through the certification process; similarly, no guarantee, implied or otherwise, is made that examination items (questions) will test knowledge contained in these publications. Nonetheless, Board Certified Nuclear Pharmacists serving on the Scientific and Professional Affairs Committee believe that information contained in these publications will enhance the knowledge base of most nuclear pharmacists. Furthermore, this bibliography may be beneficial in guiding individuals to selected information sources in self-identified areas needing review.

REGULATORY

  • 10 CFR Parts 10, 19, 20, 30, 31, 32, 33, 35, United States Nuclear Regulatory Commission, Washington, DC. (current revision)
  • 49 CFR Parts 100-177, United States Department of Transportation, Washington, DC. (current revision)
  • 21 CFR Parts 361, United States Food and Drug Administration, Washington, DC. (current revision)
  • "Nuclear Pharmacy Guideline Criteria for Determining When to Register as a Drug Establishment". United States Food and Drug Administration, Rockville, MD. (May 1984)
  • "Model Regulations for Nuclear Pharmacy". National Association of Boards of Pharmacy, Park Ridge, IL. (current revision)
  • "Accreditation Manual for Hospitals", Joint Commission on Accreditation of
  • Healthcare Organizations, Oakbrook Terrace, IL. (current revision)

PRODUCT MONOGRAPHS

  • Package inserts, various manufacturers. (current revisions)
  • Individual monographs, United States Pharmacopeia/National Formulary
  • [USP/NF], United States Pharmacopeial Convention, Rockville, MD.
  • (current revision)
  • Individual monographs, United States Pharmacopeia Dispensing Information [USP-DI], United States Pharmacopeial Convention, Rockville, MD. (current revision)

TEXTBOOKS

"Chemistry for Nuclear Medicine", M.W. Billinghurst, A.R. Fritzberg, Year Book Medical Publishers, Chicago, IL. (1991)

contains information on general, coordination, and organic chemistry; methods of separation and analysis-, laboratory safety

"Chromatography of Technetium-99m Radiopharmaceuticals", P.J. Robbins, Society of Nuclear Medicine, New York, NY. (1984)

contains information on quality control of Tc-99m Radiopharmaceuticals

"Diagnostic Interventions in Nuclear Medicine", J. Thrall, D. Swanson, Yearbook Medical Publishers, Chicago, EL. (1985)

contains information on pharmacological and physiological interventions with radiopharmaceutical studies

"Principles and Practice of Nuclear Medicine", P.J. Early, D.B. Sodee, Mosby, St. Louis, MO. (1985) [new edition expected circa 1994]

contains information on nuclear physics, radiobiology, radiation protection. dosimetry, Radiopharmaceuticals, nuclear imaging procedures

"Nuclear Pharmacy: An Introduction to the Clinical Application of Radiopharmaceuticals", H.M. Chilton, R. Witcofski, Lea & Febiger, Philadelphia, PA. (1986)

contains information on the production, procurement, compounding, quality control, dispensing, distribution, radiation protection, biodistribution. physical and chemical properties, and clinical indications and use of Radiopharmaceuticals

"Technetium in Chemistry and Nuclear Medicine, 2", M. Niclini, G. Bandoli, U. Massi, Raven Press, New York, NY. (1986) proceedings of the Second International Symposium on Technetium in Chemistry and Nuclear Medicine.

contains information on technetium chemistry. Radiopharmaceuticals labeled with technetium, and the use of technetium radiopharmaceuticals in nuclear medicine

"Essentials of Nuclear Medicine Science", W.B. Hladik, G.B. Saha, K.T. Study, Williams & Wilkins, Baltimore, MD. (1987)

contains information on the biodistribution and clinical indications and use of Radiopharmaceuticals, altered biodistribution caused by drugs. diseases. and formulation problems-. adverse reactions; research and education

"Physics in Nuclear Medicine, 2nd Edition", J.A. Sorenson, M.E. Phelps, Grune & Stratton, Orlando, FL. (1987)

contains fundamental information on physics and instrumentation

"Practical Nuclear Pharmacy, 3rd Edition", T. Phan, M. Ling, R. Wasnich, Banyan Press, Honolulu, HI. (1987)

contains information on the preparation. quality control. and biodistribution of radiopharmaceuticals; regulations

"Radiopharmaceuticals in Nuclear Medicine Practice", RJ Kowalsky, J.R. Perry, Appleton & Lange, Norwalk, CT. (1987)

contains information on the production, procurement, compounding, quality control. dispensing, distribution. radiation protection. biodistribution. physical and chemical properties. and clinical indications and use of radiopharmaceuticals

"MIRD Primer for Absorbed Dose Calculation", R. Loevinger, T.F. Budinger, E.E. Watson, The Society of Nuclear Medicine, New York, NY. (1988)

contains information on absorbed dose calculations, dosimetry estimates for several Radiopharmaceuticals

"Radiopharmaceuticals and Brain Pathophysiology Studied with PET and SPECT", M. Diksic, R.C. Reba (eds), CRC Press, Boca Raton, FL. (1990)

contains information on PET and SPECT radiopharmaceutical synthesis, biological modeling, and clinical applications

"Pharmaceuticals in Medical Imaging", D.P. Swanson, H.M. Chilton, Macmillan, New York, NY. (1990)

contains information on the chemistry, pharmacokinetics, precautions. dosage/dosimetry. clinical considerations in the use of radiopharmaceuticals

"Clinical Nuclear Medicine Science, Second Edition", M.N. Maisey, K.E. Britton, D.L. Gilday, Lippincott, Philadelphia, PA. (1991)

contains information on the clinical use of radiopharmaceuticals

"Essentials of Nuclear Medicine Imaging, Third Edition", F.A. Mettler, M.J. Guiberteau, Saunders, Philadelphia, PA. (1991)

contains information on procurement, quality control. radiation protection, clinical use of radiopharmaceuticals, and imaging techniques

"Fundamentals of Nuclear Pharmacy, Third Edition", G.B. Saha, SpringerVerlag, New York, NY. (1992)

contains information on the production, procurement. compounding, quality control. dispensing, distribution, radiation protection. biodistribution, physical and chemical properties. and clinical indications and use of radiopharmaceuticals

"Introductory Physics of Nuclear Medicine, Fourth Edition", R. Chandra, Lea & Febiger, Malvern, PA. (1992)

contains information on nuclear physics, radiation detection/imaging, radionuclide production, radiopharmaceuticals, dosimetry, radiation biology, radiation protection

"Medical Physics Handbook of Nuclear Medicine", M.T. Madsen, I.A. Ponto, Medical Physics Publishing, Madison, WI. (1992)

contains information on the physical characteristics of radionuclides. dosirnetry of radiopharmaceuticals; radiation safety guidelines and procedures

"Practical Nuclear Medicine", E. Palmer, J. Scott, H.W. Strauss, Saunders, Philadelphia, PA. (1992)

contains information on contemporary nuclear medicine practice, including the use of radiopharmaceuticals in diagnosis

"Radiopharmaceuticals: Chemistry and Pharmacology", A.D. Nunn (ed), Marcel Decker, New York, NY. (1992)

contains information on radiopharmaceutical chemistry and biodistribution

"Atlas of Nuclear Medicine Imaging, 2nd Edition", S. Baum (ed), Appleton & Lange, Norwalk, CT. (1993)

contains images of the principal organ systems of radiopharmaccutical distribution patterns in normal and various disease conditions

"Handbook of Nuclear Medicine, Second Edition", F.L. Datz, Mosby, St. Louis, MO. (1993)

contains information on anatomv. physiology. radiopliarmaccuticlis. and imaging techniques for nuclear medicine studies

"Physics and Radiobiology of Nuclear Medicine", G.B. Saha, Springer-Verlag, New York, NY. (1993)

contains inforitiation on nuclear physics, radiation detection/imaging, radionuclide production, dosimetry, radiation biology, radiation protection

"Textbook of Radiopharmacy", C.B. Sampson (ed), Gordon and Breach Science Publishers, New York, NY. (1994)

contains information on the production, procurement, compounding, quality control. dispensing, distribution, radiation protection, biodistribution, physical and chemical properties, and clinical indications and use of radiopharmaceuticals

"Pharmacologic Alterations in the Biorouting/Performance of Select Radiopharmaceuticals Used in Cardiac Imaging", D.L. Laven, J.A. Clanton, W.B. Hladik, S.M. Shaw, To order contact: Gammascan Consultants, 633 Sabal Lake Dr., Longwood, FL  32779; (407) 774-7601; email: dlavenrx@earthlink.net 

contains information on undesirable drug-radiopharmaceutical interactions; pharmacologic interventions in nuclear medicine procedures; drug therapy monitoring with nuclear medicine procedures

"Pharmacologic Alterations in the Biorouting/Performance of Select Radiopharmaceuticals Used in Nuclear Medicine Adrenal, Cerebral, Hepatobiliary, Pulmonary and Renal Scintigraphic Studies", D.L. Laven, J.A. Clanton, W.B. Hiadik, S.M. Shaw, To order contact: Gammascan Consultants, 633 Sabal Lake Dr., Longwood, FL  32779; (407) 774-7601; email: dlavenrx@earthlink.net 

contains information on undesirable drug-radiophamaceutical interactions-, pharmacologic interventions in nuclear medicine procedures-, drug therapy monitoring with nuclear medicine procedures

"Pharmacologic Alterations in the Biorouting/Performance of Select Radiopharmaceuticals Used in Nuclear Medicine Abscess Detection, Bone Marrow, Hepatic Chemoperfusion, Liver/Spleen, Skeletal, Tumor/Inflammation Imaging", D.L. Laven, J.A. Clanton, W.B. Hladik, S.M. Shaw, To order contact: Gammascan Consultants, 633 Sabal Lake Dr., Longwood, FL  32779; (407) 774-7601; email: dlavenrx@earthlink.net 

contains information on undesirable drug-radiopharmaceutical interactions; pharmacologic interventions in nuclear medicine procedures-, drug therapy monitoring with nuclear medicine procedures

"Pharmacologic Alterations in the Biorouting/Performance of Radiopharmaceuticals Used in Cisternography, Ferrokinetic Studies, Gastrointestinal Imaging, Schillings Testing, Thrombus Localization, Thyroid Uptake/Imaging, and Other Nuclear Medicine Procedures" , D.L. Laven, J.A. Clanton, W.B. Hladik, S.M. Shaw, To order contact: Gammascan Consultants, 633 Sabal Lake Dr., Longwood, FL  32779; (407) 774-7601; email: dlavenrx@earthlink.net 

    contains information on undesirable drug-radiopharmaceutical interactions; pharmacologic interventions in nuclear medicine procedures-, drug therapy monitoring with nuclear medicine procedures

CONTINUING EDUCATION PROGRAMS

    University Of New Mexico:

  • "An Update of Radiopharmaceuticals for Renal Imaging and Function Studies", Volume 1, Lesson 1.
  • "Technetium Agents and Thallium for Myocardial Perfusion Imaging", Volume 1, Lesson 2.
  • "Radiolabeled Red Blood Cells: Methods and Mechanisms", Volume 1, Lesson 3.
  • "Low-Level Exposure to Ionizing Radiation: Current Concepts & Concerns for Nuclear Pharmacists", Vol 1. Lesson 4.
  • "Scintigraphy of the Gastrointestional Tract", Volume 1, Lesson 5.
  • "The Status of Radiolabeled Antibodies for Imaging and Therapy", Volume I, Lesson 6.
  • "Radionuclide Therapy of Painful Osseus Metastses", Volume II, Lesson 1.
  • "Radiopharmaceuticals for Imaging of Infection and Inflammatory Lesions", Volume 11, Lesson 2.
  • "A Review of Radiopharmaceutical Formulation Problems and Their Clinical Manifestations", Volume II, Lesson 3.
  • "A Guide to Preparing for a Nuclear Pharmacy Inspection", Volume 11, Lesson 4.
  • "Radiopharmaceuticals for Clinical PET: Formulations and Quatilt-,v Control, Regulatory Issues, and Professional Responsibilities", Volume 11, Lesson 5.
  • "Diagnostic Imaging of Colorectal Carcinoma with Radiolabeled Monoclonal Antibodies", Volume 11, Lesson 6.
  • "Radiopharmaceuticals for the Diagnosis of Psychiatric Disorders", Volume 111, Lesson 1.
  • "The Application of Pharmacokinetic Methods to Radiopharmaceuticals", Volume 111, Lesson 2.
  • "Radiopharmaceuticals for the Scintigraphic Assessment of Hepatobiliary Function", Volume 111, Lesson 3.
  • "Pulmonary Localization of Non-Solid-Particle Radiopharmaceuticals: Clinical, Anatomic, Functional, and Therapeutic implications", Volume 111, Lesson 4.
  • "Radiochemical Purity Testing of Recently-Approved Tc-99m Radiopharmaceuticals", Volume 111, Lesson 5.
  • "Pharmacologic Enhancement of Radioimmunotherapy", Volume Lesson 6.

JOURNAL ARTICLES

Antibodies

  • "Indium-111-Monocional Antibodies in Radioimmunoscintigraphy", G.H. Hinkle, J.A. Loesch, T.L. Hill, et al., J Nucl Med Technol 18:16-28 (1990).
  • "A Practical Approach to Monoclonal Antibody Imaging", L.Trembath, B.D. Collier, W.J. Schulte, J Nucl Med Technol 21:171-176 (1993).

Brain

  • "Interventions and Functional Brain Imaging", A.P. Yudd, R.L. Van Heertum, J.C. Masdeu, Semin Nucl Med 21:153-158 (1991).
  • "Radiopharmaceuticals for Brain Imaging: The Technologist's Perspective", R.S. Tikofsky, L. Trembath, A.M. Voslar, J Nucl Med 21:57-60 (1993).

Cardiac

  • "Dipyridamole Thallium Imaging", B.K. Pounds, W.H. Moore, E.J. Ladwig, et al., J Nucl Med Technol 18:165-173 (1990).
  • "Adenosine Cardiac Imaging", T.M. Boyce, G.W. Guidry, J.J. Mahmarian, et al., J Nucl Med Technol 19:203-208 (1991).
  • "Pharmacologic Cardiac Intervention: Comparison of Adenosine, Dipyridamole, and Dobutamine", J.S. Blust, T.M. Boyce, W.H. Moore, J Nucl Med Technol 20:53-59 (1992).
  • "Myocardial Perfusion Imaging with Thallium-201:, G.A. Beller, J Nucl Med 35:674-680 (1994).
  • "Myocardial Perfusion Imaging with Technetium-99m-Sestamibi: Comparative Analysis of Available Imaging Protocols", D.S. Berman, H.S. Kiat, K.F. Van Train, et al., J Nucl Med 35:691-688 (1994).
  • "Myocardial Perfusion Imaging with Technetium-99m-Teboroxime", L.L. Johnson, J Nucl Med 35:699-692 (1994).
  • "Adenosine Myocardial Perfusion Imaging", A.S. Iskandrian, J Nucl Med 35:734-736 (1994).
  • "Pharmacologic Stress Testing: Experience with Dipyridamole, Adenosine, and Dobutamine", M.E. McGuinness, R.L.Talbert, Am J Hosp Pharm 51:329-346 (1994).

CELL LABELLING

  • "Blood Cell Labeling with 99mTc: Progress and Perspectives", S.C. Srivastava, R.F. Straub, Semin Nucl Med 20:41-51 (1990).
  • "Facilities and Equipment for Aseptic and Safe Handling of Blood Products", P. Zabel, N. Robichaud, A. Hiltz, J Nucl Med Technol 20:236-241 (1992).
  • "Personnel and Product Protection During Manipulation of Blood Products", P. Zabel, N. Robichaud, A. Hiltz, J Nucl Med Technol 21:33-37 (1993).
  • "Indium-111 Labeled Leukocytes for the Detection of Infection: Current Status", F.L. Datz, Semin Nuct Med 24:92-109 (1994).
  • "The Utility of Tc-99m HNVAO Leukocytes for Imaging Infection", A.M. Peters, Semin Nucl Med 24:110-183 (1994).

ENDOCRINE/TUMOR

  • "Parathyroid Scanning", B. Ratliff, P. Soon, S. MacFarlane, L Hanelin, J Nucl Med Technol 14:34-39 (1986).
  • "Thyroid Imaging Studies", H.H. Drew, N.D. LaFrance, J.J.S. Chen, J Nucl Med Technol 15:79-87 (1987).
  • "Labetalol Reduces Iodine-131 MIBG Uptake by Pheochromocytoma and Normal Tissues", F.A. Khafagi, B. Shapiro, L.M. Fig, et. al., j Nucl Med 30:481-489, (1989). [contains a comprehensive list of drug interactional
  • "Endocrine Imaging: Parathyroid, Adrenal Cortex and Medulla, and Other Endocrine Tumors, Part 11", W.H. Beierwaltes, J Nucl Med 32:1627-1639 (1991).
  • "Somatostatin Receptor Scintigraphy with [Illln-DTPA-D-Phel- and [1231-Tyri- Octreotide: the Rotterdam Experience with More than 1000 Patients", E.P. Krenning, D.J. Kwekkeboom, W.H. Bakker, et. al., Eur J Nucl Med 20:716-731 (1993).

GI TRACT

  • "Physiological and Pharmacological Interventions in Radionuclide Imaging of the Tubular Gastrointestinal Tract", F.L. Datz, P.E. Christian, W.R. Hutson, et al., Semin Nucl Med 21: 140-152 (I 99 1).

KIDNEY

  • "99mTc Renal Tubular Function Agents: Current Status", D. Eshima, A.R. Fritzberg, A. Taylor, Semin Nucl Med 20:28-40 (1990).
  • "Interventions in Renal Scintigraphy", E.J. Fine, Semin Nucl Med 21:116-127 (1991).

LIVER/HEPATOBILIARY

  • "Augmented Cholescintigraphy: Its Role in Detecting Acute and Chronic Disorders of the Hepatobiliary Tree", D. Fink-Bennett, Semin Nucl Med 21:128-139 (1991).
  • "Hepatobiliary Imaging Update", M. Chester, J. Glowniak, J Nucl Med Technol 20:3-7 (1992).

LUNG

  • "Evaluation of Pulmonary Embolism-Role of Lung Scanning", R.A Blinder, J Nucl Med Technol 16:14@-149 (1988).

PET

  • "PET Cancer Evaluations with FDG", R.A. Hawkins, C. Hoh, M. Dalbom, et al., J Nucl Med 32:1555-1557 (1991).
  • "Principles and Clinical Applications of Positron Emission
  • Tomography", S.F. Gardner, J.A. Green, E.M. Badnarczyk, et al., Am J Hosp Pharm 49:1499-1506 (1992).
  • "Myocardial Perfusion Imaging with PET", M. Schwaiger, J Nucl Med 35:693-698 (1994).

OUALITY CONTROL

  • "Quality Control Procedures for Newer Radiopharmaceuticals", A.M. Zimmer, S.M. Spies, J Nucl Med Technol 19:210-214 (1991).
  • "Technetium-99m MAG3: Labeling Conditions and Quality Control", D.L. Nosco, R.G. Wolfangel, M.J. Bushman, et al., J Nucl Med Technol 21:69-74 (1993).

THERAPY

  • "Radioimmunotherapy with Monoclonal Antibodies", C.M. Suey, G.L. DeNardo, S.J. DeNardo, A.H. Gobuty, J Nucl Med Technol 19:176-183 (1990).
  • "Iodine-131 as an Oncology Agent", J.M. Bender, H.J. Dworkin, J Nucl Med Technol 21:140-150 (1993).
  • "Radionuclide Therapy of Osseous Metastatic Disease", M.T. Clarke, E. Galie, J Nucl Med Technol 21:3-6 (1993).
  • "Strontium-89 Therapy in Painful Bony Metastases", C.Z. Dickinson, N.S. Hendrix, J Nucl Med Technol 21:133-137 (1993).